Travocort is a combination cream containing an antifungal and a potent steroid. It is used for fungal skin infections that are also markedly inflamed and itchy — and it is a short-course product, because the steroid in it should not be continued once the inflammation settles.

What is Travocort?

The South African Medicine Price Registry lists Travocort as a Schedule 4 cream containing:

IngredientAmountWhat it does
Isoconazole nitrate10 mg/g (1%)Antifungal
Diflucortolone valerate1 mg/g (0.1%)Potent corticosteroid

Isoconazole is an azole antifungal. Fungal cell membranes depend on ergosterol, which human cells do not use; isoconazole blocks the enzyme that makes it, so the fungal membrane fails. It also has some activity against certain gram-positive bacteria.

Diflucortolone valerate is a potent topical steroid — in the same strength class as betamethasone, and considerably stronger than hydrocortisone. It reduces the redness, swelling and intense itch that a heavily inflamed fungal infection produces.

The combination exists for a specific and genuinely useful situation. A fungal infection in a warm moist site — the groin, under the breasts, between the toes — can become so inflamed and itchy that scratching breaks the skin and the person cannot tolerate an antifungal alone. Adding a steroid settles the inflammation quickly so treatment becomes bearable.

But it is a short-term measure, not the treatment. The steroid suppresses the immune response that helps contain the fungus, so using it for too long lets the infection spread while masking the redness. That produces tinea incognito — a fungal rash altered by steroid use into something larger, less typical and harder to recognise.

The typical approach is a couple of weeks on the combination, then switching to a plain antifungal to complete the course. If nobody explained that, it is worth asking.

What is Travocort commonly used for?

What it is not for:

On the “ringworm” question, which is a common search: Travocort does treat ringworm, because it contains an antifungal. But for straightforward ringworm a plain antifungal is preferable — the steroid adds nothing you need and risks the infection spreading if used beyond a short period.

How Travocort fits into this medicine category

GroupExamplesUse
Antifungal + potent steroidTravocortMarkedly inflamed fungal infection, short courses
Plain antifungalsClotrimazole (Canex V), miconazole, terbinafineFungal infection — the mainstay
Potent steroidsBetamethasone (Clomaderm), mometasoneInflammation without infection
Mild steroidsHydrocortisone 1%Mild eczema, face, folds
Antibiotic + steroidFusidic acid with hydrocortisoneInflamed bacterially infected skin
Oral antifungalsFluconazole, terbinafineNail, scalp and extensive infection

See the skin and wound care hub.

What to check before using Travocort

Use it only on skin a clinician has assessed, and only for the period prescribed — usually about two weeks.

Tell your doctor or pharmacist if:

Using it:

Possible cautions and when to ask a pharmacist or doctor

Common effects are burning, stinging, itching or dryness where applied.

Prolonged use brings the potent steroid’s effects, particularly in folds where skin is thin and occluded:

Stop and seek advice if the treated skin becomes thinner or shinier, if stretch marks or visible vessels appear, or if the rash spreads or changes character on treatment.

Get emergency help for swelling of the face, lips or tongue, difficulty breathing, or a rapidly spreading blistering rash.

Contact your doctor if:

Related medicine guides

Frequently asked questions

What is Travocort cream used for? Fungal skin infections that are markedly inflamed and itchy — jock itch, athlete’s foot, ringworm and skin-fold infections. It contains an antifungal and a potent steroid.

Is Travocort used for ringworm? It does treat ringworm, because it contains an antifungal. For straightforward ringworm a plain antifungal is preferable — the steroid adds nothing you need and risks the infection spreading if used too long.

Is Travocort used for rashes generally? No. It should only be used on a rash a clinician has assessed as a fungal infection with inflammation. Using a combined steroid on an undiagnosed rash obscures the diagnosis.

How long can I use it? Usually about two weeks, then switch to a plain antifungal to finish the course. Ask your prescriber what to switch to.

Why can’t I keep using it? The steroid suppresses the immune response that contains the fungus, so prolonged use lets the infection spread while masking the redness.

Can I use it on my face? Only on medical advice and briefly. The steroid in it is potent, and facial skin thins quickly.

Can I use it on nails or scalp? No. Creams cannot penetrate nails or reach hair follicles. Those need oral treatment.

Why does my rash look odd now? Prolonged steroid use on a fungal infection produces tinea incognito — an altered, less typical rash. See a doctor.