Used For

Espiride Used For

Espiride (sulpiride) is primarily used to treat schizophrenia and other psychotic disorders, as well as depressive conditions such as dysthymia, reactive depression, and depression associated with psychoses of other origins[1][2][3][4][5][6][7][8].

It can be used alone or as adjunctive therapy in schizophrenia (including both acute and chronic types), especially when symptoms include hallucinations, autism, aggressiveness, or withdrawn/inhibited behavior[1][3][4][5][6][7]. Espiride has also been prescribed for:

  • Depression (including dysthymia and depressive psychoses)[1][2][3][4][5]
  • Anxiety disorders or panic disorder[2][3][4]
  • Obsessive-compulsive disorder[2][4]
  • Phobia and post-traumatic stress disorder[2][4]
  • Behavior disorders with abnormal aggression[5]
  • As adjunct in the management of physical conditions, like duodenal ulcers of psychosomatic origin[5]
  • Other disorders, including some cases of senile dementia, transient psychosis following surgery or myocardial infarction, and as an antiemetic in select countries[3][7]

Espiride is available in oral formulations and acts as a selective D2 dopamine receptor antagonist to control psychotic symptoms and regulate mood[2][4][6]. It may also be used off-label for some treatment-resistant affective or anxiety conditions, as well as for adjunctive antidepressant therapy[1][3].

References

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