Sensahist contains cetirizine dihydrochloride 10 mg, a once-daily non-sedating antihistamine. It treats hay fever, allergic rhinitis, itchy watery eyes, hives and allergic itching. It is among the most effective antihistamines for itching, with far less drowsiness than older ones.

What is Sensahist?

Sensahist contains cetirizine dihydrochloride 10 mg, a second-generation antihistamine. It is a Schedule 2 medicine.

An allergic reaction begins when the immune system treats something harmless — pollen, dust mite, mould, animal dander — as a threat. Mast cells release histamine, and histamine acting on H1 receptors produces the familiar cluster: sneezing, a runny itchy nose, watery eyes, and in the skin, weals and itching. Cetirizine occupies those receptors so histamine cannot bind.

Older antihistamines such as the chlorphenamine in Allergex cross readily into the brain, where the same receptors govern wakefulness, and cause pronounced drowsiness. Cetirizine was designed to cross far less, which makes a once-daily antihistamine practical for someone who has to drive, work or study.

Within that group, cetirizine sits usefully: it is among the most effective for itching and for hives, though it sedates slightly more than loratadine. For most people that trade favours cetirizine.

The same ingredient is sold under many names — Cetirizine, Austell Cetirizine, Seasoneze, Allecet, Zelary, Trantrin, Zyrtec and Sensahist among them. They are one medicine, and taking two together simply doubles the dose.

What is Sensahist commonly used for?

For hives, cetirizine deserves particular mention. Chronic urticaria is often treated with a second-generation antihistamine at higher than the standard once-daily amount — sometimes considerably higher — under medical supervision, and this works well for many people. Do not increase it yourself, but if standard treatment is not controlling hives, it is worth asking a doctor about, because many people give up assuming nothing more can be done.

For seasonal allergy, start before the season. An antihistamine blocks histamine from binding but does not reverse a reaction already established. Taking it daily from a week or two beforehand gives noticeably better control than reacting to bad days.

It does not treat a cold, which is viral, and it does not treat asthma.

For blocked nose, a steroid nasal spray works considerably better, since congestion is driven more by inflammation than by histamine.

How Sensahist fits into this medicine category

GroupExamplesNote
Second-generation antihistaminesCetirizine (Sensahist, Seasoneze), loratadine (Lorfast), fexofenadineOnce daily; little drowsiness
First-generation antihistaminesChlorphenamine (Allergex, Rhineton)Effective; markedly sedating
Steroid nasal spraysFluticasone, mometasoneBest for congestion; work over days
DecongestantsPseudoephedrine, oxymetazolineShort-term only; rebound with overuse
Eye dropsSodium cromoglycate, antihistamine dropsTargeted relief for itchy eyes

See the allergy, cold and flu medicines hub.

What to check before using Sensahist

Take one tablet once daily, at any time, with or without food.

Do not take it with another antihistamine. This matters more than people expect, because cetirizine is sold under so many names and also appears in combination allergy and cold products. Check the active ingredients.

Speak to a pharmacist or doctor if:

Avoid alcohol until you know how it affects you.

Follow the pack instructions. This page does not set doses.

Possible cautions and when to ask a pharmacist or doctor

A minority do feel drowsy. If you are one of them, take it in the evening, or ask a pharmacist about loratadine or fexofenadine, which sedate less. Do not drive until you know how you respond.

Dry mouth, headache and tiredness are the other common effects, usually mild.

Do not stop suddenly after long continuous use. A withdrawal itch — intense generalised itching lasting days to weeks after stopping — is recognised in people who have taken cetirizine daily for months or years. It is uncommon and it resolves, but it catches people out badly because it looks like the allergy returning far worse. Taper rather than stopping outright.

If it is not helping, something else is going on. Persistent symptoms despite a daily antihistamine may mean congestion is the dominant problem, that the trigger is not allergic, or that additional treatment is needed.

Reducing exposure helps: dust mite covers on mattress and pillows, windows shut at high pollen times, showering after being outdoors, drying laundry indoors in pollen season, and keeping pets out of bedrooms.

Seek urgent medical attention for swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, wheezing, faintness with a widespread rash, or a rash that blisters or peels. Hives with any swelling of the mouth or throat is an emergency.

Related medicine guides

Frequently asked questions

What is Sensahist 10 mg used for? Hay fever and allergic rhinitis, itchy watery eyes, hives and allergic itching. It contains cetirizine.

Is it the same as Zyrtec or Seasoneze? The active ingredient is the same — cetirizine 10 mg. Brands differ, and they must not be combined.

Will it make me drowsy? Far less than older antihistamines, though a minority notice it. Take it in the evening if so.

How is it different from loratadine? Cetirizine is somewhat more effective for itching and hives; loratadine sedates even less. Both are once daily.

Can I take more than one a day for hives? Not on your own. Higher amounts are used for chronic hives, but only under medical supervision — ask your doctor.

Can I just stop after taking it for years? Taper rather than stopping outright. A withdrawal itch is recognised after long continuous use — temporary, but easily mistaken for the allergy worsening.