Adco Contromet tablet contains metoclopramide hydrochloride as its active ingredient and is primarily used for several conditions related to the digestive system and prevention of nausea and vomiting[1]:
- Prevention and treatment of nausea and vomiting, including those caused by chemotherapy, postoperative recovery, irradiation sickness, and migraine[1].
- Treatment of gastroparesis (delayed gastric emptying), especially in people with diabetes[1].
- Gastroesophageal reflux disease (GERD) that has not responded to other treatments[1].
- Augmentation of lactation (increasing breast milk production), though evidence for effectiveness is poor[1].
- Facilitation of radiological examinations (such as X-ray of the stomach or duodenum) by improving gastric emptying[2].
Metoclopramide works by increasing the motility (movement) of the upper gastrointestinal tract, helping food move more efficiently from the stomach into the intestine, and by blocking dopamine receptors in the brain and gut to reduce nausea and vomiting[4]. Usage of Adco Contromet is typically short-term due to the risk of side effects such as tardive dyskinesia with prolonged use[2].
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