Yaz Plus is primarily used as a birth control pill to prevent pregnancy, and it is also indicated for the treatment of moderate acne vulgaris in women aged 14 and older who have reached menarche and can use oral contraceptives[1]. In addition to its contraceptive function, Yaz Plus may be used to help address symptoms associated with premenstrual dysphoric disorder (PMDD) and support folate levels in women using this formulation as it contains levomefolate calcium, a biologically active form of folic acid[1][7].
Yaz Plus contains two synthetic female hormones: drospirenone (a progestin) and ethinyl estradiol (an estrogen), alongside levomefolate calcium, a vitamin B9 derivative[1][7]. The addition of levomefolate helps maintain adequate folate levels, which is important as oral contraceptives may decrease natural folate levels in the body[7].
The main uses for Yaz Plus are:
- Prevention of pregnancy (contraception)
- Treatment of moderate acne vulgaris in women age 14 or older who desire oral contraception
- Supplementation with levomefolate calcium to support folate status while using oral contraceptives
Yaz Plus prevents pregnancy through several mechanisms, including inhibiting ovulation (egg release) and changing the cervical mucus to make it more difficult for sperm to reach the egg[7]. The synthetic hormones in Yaz Plus closely mimic the natural hormones produced by the body, while the levomefolate calcium component provides an active form of folic acid that supports normal cellular functions, particularly in women who might otherwise develop folate deficiency while on oral contraceptives[7].
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